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Sriyash Mangal on Muck Rack

Sriyash Mangal

As seen in: Color Research & Application, Wiley, BioRxiv
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Articles

Spatially distinct inputs modulate the amount of active Mitotic-phase GAP to locally restrict RhoA signaling for successful cell division

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By Friederike Wolff, Swathi Srinivasan, Sriyash Mangal, Marie Christin Nöcker
| BioRxiv
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Light‐Controlled Cell‐Cycle Arrest and Apoptosis

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By Edgar Uhl, Friederike Wolff, Sriyash Mangal, Henry Dube
| Color Research & Application Verified
Cover Picture Prof. Dr. Henry Dube Ludwig-Maximilians-Universität München, Department of Chemistry and Center for Integrated Protein Science CIPSM, Butenandtstr. 5–13, 81377 München, Germany Current address: Friedrich-Alexander-Universität Erlangen-Nürnberg, Department of Chemistry and Pharmacy, Nikolaus-Fiebiger-Str.
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Light‐Controlled Cell‐Cycle Arrest and Apoptosis

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By Edgar Uhl, Friederike Wolff, Sriyash Mangal, Henry Dube
| Color Research & Application Verified
Abstract Cell‐cycle interference by small molecules has widely been used to study fundamental biological mechanisms and to treat a great variety of diseases, most notably cancer. However, at present only limited possibilities exist for spatio‐temporal control of the cell cycle. Here we report on a photocaging strategy to reversibly arrest the cell cycle at metaphase or induce apoptosis using blue‐light irradiation.
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