Stanton Nielsen

Keywords antibody production, diversification, humanized mice, immune response Department Microbiology and Molecular Biology Abstract Many scientists are skeptical of using humanized mice to study the human adaptive immune response. The reasoning behind this skepticism stems from discrepancies in various studies seen previously. A study conducted by Traggiai et al. showed that humanized mice elicited a human adaptive immune response when challenged with the tetanus toxin (Traggiai).

The major risk of the carotid artery stenting (CAS) procedure involves stroke occurring during or immediately after the procedure. TransCarotid Artery Revascularization (TCAR) was developed to avoid aortic arch and using flow reversal to reduce stroke, which has the potential to make stenting of equivalent safety to carotid endarterectomy. In this study we compared the radiation exposure between TCAR and traditional transfemoral CAS procedures.