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Articles

Efficacy and safety of an mRNA-based RSV preF vaccine in preclinical studies

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By Qin Li, Rongkuan Hu, Starna Therapeutics
| biorxiv.org
Abstract The transmembrane fusion (F) protein of RSV plays important roles in RSV pathogenesis as it mediates the fusion between virus and the target cell membrane. During the fusion process, F protein transits from a metastable state (prefusion, preF) to a stable state after merging of virus and cell membranes (postfusion, postF).
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