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Stefania Alexandra Iakab on Muck Rack

Stefania Alexandra Iakab

As seen in: Nature
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Articles

Deep MALDI-MS spatial omics guided by quantum cascade laser mid-infrared imaging microscopy - Nature Communications

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By Lars Gruber, Stefan Schmidt, Thomas Enzlein, Huong Vo, James Cairns, Denis Abu Sammour, Omar Sharif, Gernot Schabbauer, Rüdiger Rudolf, Matthias Eckhardt, Stefania Alexandra Iakab, Laura Bindila, Tobias Bausbacher
| Nature Verified
Abstract In spatial’omics, highly confident molecular identifications are indispensable for the investigation of complex biology and for spatial biomarker discovery. However, current mass spectrometry imaging (MSI)-based spatial ‘omics must compromise between data acquisition speed and biochemical profiling depth.
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TET3 regulates terminal cell differentiation at the metabolic level - Nature Communications

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By Daniela Gerovska, Guangming Wu, Daniel Jimenez-Blasco, F. Thomas Wunderlich, Juan Pedro Bolaños, Carsten Hopf, José Antonio Enríquez, Marcos J Araúzo-Bravo, Stefania Alexandra Iakab
| Nature Verified
Abstract TET-family members play a critical role in cell fate commitment. Indeed, TET3 is essential to postnatal development due to yet unknown reasons. To define TET3 function in cell differentiation, we have profiled the intestinal epithelium at single-cell level from wild-type and Tet3 knockout mice. We have found that Tet3 is mostly expressed in differentiated enterocytes.
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