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Stefano Longobardi

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Articles

A model for the human fetal ventricular myocyte electrophysiology

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By Stefano Longobardi, Anita Alvarez-Laviada, Adelisa Avezzú
| PLOS
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Avezzú A, Longobardi S, Alvarez-Laviada A, Schultz F, Gorelik J, Williamson C, et al. (2026) A model for the human fetal ventricular myocyte electrophysiology. PLoS Comput Biol 22(1): e1013889. https://doi.org/10.1371/journal.pcbi.1013889 Editor: Haibo Ni, Nanjing University, CHINA Received: May 20, 2025; Accepted: January 5, 2026; Published: January 27, 2026 Copyright: © 2026 Avezzú et al.
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Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators

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By Marina Strocchi, Christoph M. Augustin, Stefano Longobardi
| PLOS
Sensitivity analysis and history matching on simulator components Tables 1–3 list all parameters we initially considered. Excluding the values we could derive from the available clinical data, the total number of parameters was 117. This means that we would need to run over 1000 simulations for GPE training, which constitutes a considerable computational cost.
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