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Stephen Couban

As seen in: The Lancet
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Articles

Addition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label

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By Irwin Walker, Tony Panzarella, Stephen Couban
| The Lancet Verified
Summary Background Previous trials testing prevention strategies for chronic graft versus host disease (GVHD) have measured its cumulative incidence. In this trial of anti-thymocyte globulin, we measured treatment-independence at a long-term timepoint as the primary endpoint. Methods This was a randomised, open-label, multicentre, phase 3 trial done at ten centres in Canada and one in Australia.
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