Stephen Jun Fei on Muck Rack

Stephen Jun Fei

As seen in: Molecular Cancer
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BCL-2 dependence is a favorable predictive marker of response to therapy for chronic lymphocytic leukemia - Molecular Cancer

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By Jie Qing, Li Ren, Boon Cher, Stephen Jun Fei
| Molecular Cancer Verified
Overall apoptotic priming and functional dependence correlate with distinct molecular features As the heterogeneity of ex vivo drug responses in CLL has been found to be partly explained by the genomic background of patient samples [7], we first evaluated whether differences in mitochondrial priming and functional dependence on BCL-2 family anti-apoptotic proteins could complement genomic data to better understand this variation.
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