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Articles by Stephen Tomlin
‘Harmful’ or ‘excipients of concern’? Rethinking terminology and risk in pediatric excipients
ABSTRACT Introduction Excipients, though often overshadowed by active pharmaceutical ingredients, are essential for the successful formulation of medicinal products. They serve critical roles, such as enhancing drug stability, ensuring proper delivery, and facilitating patient compliance. However, the perception of excipients has become increasingly polarized, with some being labeled as ‘Harmful’ or ‘Dangerous’ without a thorough and balanced analysis of contributing factors.
‘They Take the Mum Off You When You Come In’: An Ethnographic Study of Parent Experiences of Medicines Safety Systems in English Hospitals
1 Introduction Medication safety is a continuing challenge for healthcare systems. It is estimated that 6% of patients suffer severe avoidable harm during their care, and 25% of these events are related to medication [1]. Harm is common among hospitalised children, and is estimated to currently affect between one and two per cent of patients [2].
Real-World Evidence of 3D Printing of Personalised Paediatric Medicines and Evaluating Its Potential in Children with Cancer: A Scoping Review
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Prescribing unlicensed and off-label medicines
By the end of this article, you should be able to: Define unlicensed and off-label medicines and explain their differences; Describe the when prescribing these medicines; Identify for unlicensed products; Apply to ensure safe prescribing and monitoring; Recognise where off-label or unlicensed use occurs. Prescribing unlicensed and off-label medicines remains a common practice across both paediatric and adult clinical settings.
Oral liquid medicines for children: the issues of choice
Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. Neonatology Paediatrics Offering choices allows accommodation of patient preferences.
For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review
Abstract Objective Every year, medication errors harm children in hospitals. Ward rounds are a unique opportunity to bring information together and plan management. There is a need to understand what strategies can improve medication safety on ward rounds. We systematically reviewed published interventions to improve prescribing and safety of medicines on ward rounds. Design Systematic review of randomised controlled trials and observational studies. Setting Studies examining inpatient ward rounds.
For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review
http://orcid.org/0000-0002-7887-3640Charlotte King1, Jan Dudley2, Abigail Mee3, Stephen Tomlin4, http://orcid.org/0000-0003-3175-1475Yincent Tse5, http://orcid.org/0000-0001-9852-9874Ashifa Trivedi6, Daniel B Hawcutt1,7 on behalf of the Royal College of Paediatrics and Child Health/Neonatal and Paediatric Pharmacist Group Joint Standing Committee on Medicines 1 Department of Women and Child's Health, University of Liverpool Faculty of Health and Life Sciences, Liverpool, UK 2 Department of...
For children admitted to hospital, what interventions improve medication safety on ward rounds? A systematic review
http://orcid.org/0000-0002-7887-3640Charlotte King1, Jan Dudley2, Abigail Mee3, Stephen Tomlin4, http://orcid.org/0000-0003-3175-1475Yincent Tse5, http://orcid.org/0000-0001-9852-9874Ashifa Trivedi6, Daniel B Hawcutt1,7 on behalf of the Royal College of Paediatrics and Child Health/Neonatal and Paediatric Pharmacist Group Joint Standing Committee on Medicines 1Department of Women and Child's Health, University of Liverpool Faculty of Health and Life Sciences, Liverpool, UK 2Department of...
Gastro-oesophageal reflux disease in children: identification and management
How to identify the signs and symptoms of gastro-oesophageal disease in children and young people and the available treatment options. Paediatrics Gastro-oesophageal reflux (GOR) is the involuntary passage of gastric contents into the oesophagus[1]. In children, it is often a simple physiological phenomenon — especially in infants in cases of regurgitation that appear to happen unnoticed by the child.
P07 Hormonal contraceptives: safe for use in adolescent girls?
ABSTRACTS FROM THE NEONATAL AND PAEDIATRIC PHARMACISTS CONFERENCE 2021 The 27th annual conference was held virtually on 11th and 12th November 2021 Oral presentations P07 Hormonal contraceptives: safe for use in adolescent girls?
P47 Extent of paediatric exposure to pharmaceutical excipients: an exploratory study
Abstracts from the Neonatal and Paediatric Pharmacists Conference November 2019 Sutton Coldfield, UK P47 Extent of paediatric exposure to pharmaceutical excipients: an exploratory study Free Mohammed AbouDaya1, Stephen Tomlin2, Asia N Rashed3 1Evelina London Children’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust, UK 2Great Ormond Street Hospital for Children NHS Foundation Trust, UK 3King’s College London, UK; Evelina London Children’s Hospital, Guy’s and St Thomas’ NHS Foundation...
P46 Dose-banding limits for commonly prescribed medications for children in the UK
Abstracts from the Neonatal and Paediatric Pharmacists Conference November 2019 Sutton Coldfield, UK P46 Dose-banding limits for commonly prescribed medications for children in the UK Free Asia N Rashed1, Stephen Tomlin2 1King’s College London, UK; Evelina London Children’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust, UK 2Great Ormond Street Hospital for Children NHS Foundation Trust, UK Abstract Aim Currently, majority of prescribed medication doses are calculated according to a...
Mapping the prevalence and nature of drug related problems among hospitalised children in the United Kingdom: a systematic review
Abstract Background Problems arising from medicines usage are recognised as a key patient safety issue. Children are a particular concern, given that they are more likely than adults to experience medication-related harm. While previous reviews have provided an estimate of prevalence in this population, these predate recent developments in the delivery of paediatric care.
Impact of the e‐prescribing system on the incidence and nature of drug‐related problems in children in a Saudi hospital
The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Short Communication Impact of the e‐prescribing system on the incidence and nature of drug‐related problems in children in a Saudi hospital Asia N.
Evaluation of the practice of dose‐rounding in paediatrics
The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Short Communication Evaluation of the practice of dose‐rounding in paediatrics Asia N.
Deprescribing in paediatrics
Polypharmacy in paediatrics is not as common as in adults and for various reasons deprescribing is not as straightforward. There are inevitably cases whereby we have complex patients on multiple medicines, for example, complex neurological patients on drugs for dystonia, sedation, spasms, drooling and reflux. Medicines often need trialling to see if they work and we may enter a situation whereby the patient is on multiple medicines that may need rationalising.
The feasibility of using dose-banded syringes to improve the safety and availability of patient-controlled opioid analgesic infusions in children
Opioid infusions are essential therapy for children in severe pain. Patient controlled analgesia (PCA) is an attractive treatment option because of the multiple benefits it provides: immediate and effective pain relief, titration of analgesia and empowerment of the patient (or nurse) to have a degree of control over their pain which helps to retain autonomy and decrease anxiety. However, opioid infusions for children carry a high risk of medication error.
Deprescribing in paediatrics
Polypharmacy in paediatrics is not as common as in adults and for various reasons deprescribing is not as straightforward. There are inevitably cases whereby we have complex patients on multiple medicines, for example, complex neurological patients on drugs for dystonia, sedation, spasms, drooling and reflux. Medicines often need trialling to see if they work and we may enter a situation whereby the patient is on multiple medicines that may need rationalising.
Current practice of preparing morphine infusions for nurse/patient-controlled analgesia in a UK paediatric hospital: healthcare professionals’ views and experiences -- Rashed et al. -- European Journal of Hospital Pharmacy
Objective To explore the views and experiences of healthcare professionals (HCPs) regarding the preparation of morphine infusions for nurse/patient-controlled analgesia (N/PCA). Methods Three focus groups were conducted with HCPs (anaesthetists, nurses in theatres and wards) at one UK children's hospital. Focus groups were transcribed verbatim and content analysis was used to identify themes. Results A variety of approaches are used to prepare morphine infusions.
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