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Stephen Williams

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Articles

Investigating the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences - Molecular Psychiatry

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By Bill Deakin, Elizabeth Liddle, Adriana Anton, Naghmeh Nikkheslat, John Evans, Bernard Lanz, James Walters, Krish Singh, Stephen Williams, Silke Conen
| Nature Verified
Abstract We investigated the longstanding idea that the onset of psychotic symptoms in schizophrenia arises from an early phase of glutamate neurotoxicity, possibly related to loss of GABA restraint, oxidative stress or inflammation, that cumulatively results in a later phase of synaptic loss in keeping with magnetic resonance spectroscopy (MRS) evidence of reduced glutamate in schizophrenia, especially in older patients.
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Syntheses, Structures, Reactivity, and Catalytic Applications of Enantiopure Rhenium-Containing P-Stereogenic Phosphonium Salts, Phosphines, Phosphine Boranes, and Phosphine Oxides

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By Florian Seidel, Kriti Pathak, Stephen Williams, Frank Hampel
| ACS Publications
1. Introduction Click to copy section linkSection link copied! As superbly documented in a recent comprehensive review, P-stereogenic phosphorus ligands have had an immense impact in enantioselective catalysis.
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Syntheses, Structures, Reactivity, and Catalytic Applications of Enantiopure Rhenium-Containing P-Stereogenic Phosphonium Salts, Phosphines, Phosphine Boranes, and Phosphine Oxides

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By Florian Seidel, Kriti Pathak, Stephen Williams, Frank Hampel
| dx.doi.org
1. Introduction Click to copy section linkSection link copied! As superbly documented in a recent comprehensive review, P-stereogenic phosphorus ligands have had an immense impact in enantioselective catalysis.
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