Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Highlights • Engineered human microlivers enable robust long-term nucleic acid-mediated silencing • Human microlivers support assessment of hepatic-targeted nucleic acid-based therapies • siRNA-mediated silencing effectively modifies hepatocyte drug metabolism Summary The liver plays a central role in metabolism; however, xenobiotic metabolism variations between human hepatocytes and those in model organisms create challenges in establishing functional test beds to detect the potential drug...
The op234 allele was originally isolated in a forward genetic screen designed to identify novel genes that control germ line apoptosis (gla). op234 was originally assigned to a novel gene name “gla-1” as it did not map to any previously known cell death gene [24]. Through classical two- and three-factor as well as SNP mapping, we localised the allele op234 to a roughly 46 kb region containing 12 genes on chromosome I (see Materials and methods).
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
