Su Ee Tan on Muck Rack

Su Ee Tan

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Articles

Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing - Nature Communications

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By David Strutt, Su Ee Tan
| Nature Verified
Abstract Planar polarity establishment in epithelia requires interpretation of directional tissue-level information at cellular and molecular levels. Mechanical forces exerted during tissue morphogenesis are emerging as crucial tissue-level directional cues, yet the mechanisms by which they regulate planar polarity are poorly understood. Using the Drosophila pupal wing, we confirm that tissue stress promotes proximal-distal (PD) planar polarity alignment.
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