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Su Naz Mutlu on Muck Rack

Su Naz Mutlu

As seen in: Nature
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Articles

A high-throughput 3D conjunctival spheroid model for standardized in vitro testing

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By Zhi Liang, Muhammad Usman Aslam, Philipp Stahlhut, Raoul Verma-Fuehring, Ingrid Zahn, Friedrich P Paulsen, Jürgen Groll, Jost Hillenkamp, Taufiq Ahmad, Malik Salman Haider, Wahaj Ul Haq, Martina Wiesler, Su Naz Mutlu
| Nature Verified
Abstract New Approach Methodologies (NAMs) based on human cells are increasingly needed to improve the physiological relevance, reproducibility, and ethical acceptability of preclinical ocular surface research. We developed a reproducible and scalable three-dimensional in vitro conjunctival spheroid model using primary human conjunctival epithelial cells and conjunctival fibroblasts as a human-relevant, scaffold-free test system.
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