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Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue

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By Schindler TH, Mitchell JD, Sudlow LC, Berezin MY
| ncbi.nlm.nih.gov
This is a preprint. It has not yet been peer reviewed by a journal. The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed. Display options Abstract Oxaliplatin is a platinum-based alkylating chemotherapeutic agent used for cancer treatment. At high cumulative dosage, the negative effect of oxaliplatin on the heart becomes evident and is linked to a growing number of clinical reports.
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