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Suharto Banerjee on Muck Rack

Suharto Banerjee

As seen in: BioRxiv
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Articles

Mapping DHPS Evolvability: Identification of Novel Evolutionarily Critical Sub-Structure through Evolutionary and Structural Analyses of DHPS

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By Vladimir N. Uversky, Dwipanjan Sanyal, Suharto Banerjee, Aneesh Chivukula
| BioRxiv
Abstract Protein evolution shapes pathogen adaptation-landscape, particularly in developing drug resistance. The rapid evolution of target proteins under antibiotic pressure leads to escape mutations leading to the problem of antibiotic resistance. A deep understanding of the evolutionary dynamics of antibiotic target proteins presents a plausible intervention strategy for disrupting the evolutionary trajectory of resistance.
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