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Suhasini D. Lulla on Muck Rack

Suhasini D. Lulla

As seen in: The American Journal of Human Genetics
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Articles

Distinct mutational landscapes for germline and somatic cancer variants in forty tumor suppressor genes

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By Deborah I. Ritter, Chimene A Kesserwan, Sharon E. Plon, Suhasini D. Lulla
| The American Journal of Human Genetics Verified
Results To investigate whether the germline and somatic variant landscapes are congruent, we assessed the extent of overlap of unique variants. The extracted, filtered, and harmonized dataset described in the methods comprised 32,941 unique P/LP germline coding variants from ClinVar and 12,907 unique O/LO somatic coding variants in tumor specimens from cBioPortal (Figure 1B) in the 40 selected TSGs with sufficient data.
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