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Abstract Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition. Although the gut microbiome has been implicated in ASD, prior studies have insufficiently addressed clinical heterogeneity. Here, we perform shotgun metagenomic sequencing on stool samples from 720 children with ASD (median age 8 years, 87% male) and 151 matched controls.
Abstract Neurodegenerative diseases (NDDs) are characterized by neuronal damage and progressive loss of neuron function. Microbiome-based interventions, such as dietary interventions, biotics, and fecal microbiome transplant, have been proposed as a novel approach to managing symptoms and modulating disease progression.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.