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Sujeesh Sebastian on Muck Rack

Sujeesh Sebastian

Lund
As seen in: Wiley Online Library, The Journal of Arthroplasty
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Articles

Beyond Gram-Negative and Gram-Positive Bacteria: Virulence as a Determinant of Clinical Outcome in Periprosthetic Joint Infections

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By Michael Ogon Laboratory, Sujeesh Sebastian, Veronika Achatz
| The Journal of Arthroplasty Verified
Keywords Periprosthetic joint infections arthroplasty gram-negative gram-positive virulence Introduction Periprosthetic joint infections (PJIs) represent one of the most severe complications following total joint arthroplasty, often resulting in high re-revision rates and increased mortality (1,2). A variety of patient-dependent and surgical factors influence the outcomes of PJI treatment. Additionally, the causative microorganisms significantly impact long-term treatment success.
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Hydroxyapatite: An Antibiotic Recruiting Moiety for Local Treatment and Prevention of Bone Infections

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By Jintian Huang, Yang Liu Verified, Sujeesh Sebastian, Orthopedics Lund LundSweden
| Wiley Online Library Verified
Abstract Treatment of chronic osteomyelitis by radical debridement and filling of the dead space with antibiotic containing calcium sulphate/hydroxyapatite (CaS/HA) bone substitute has shown excellent long-term outcomes. However, in extensive infections, sessile bacteria may remain in bone cells or soft tissues protected by biofilm leading to recurrences.
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