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Articles

The fitness cost of a congenital heart defect shapes its genetic architecture

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By Ehiole O Akhirome, Suk Dev Regmi, Rachel Magnan, Nelson Ugwu
| BioRxiv
New Results Ehiole O Akhirome, Suk Dev Regmi, Rachel Magnan, Nelson Ugwu, Yidan Qin, Claire E Schulkey, James M Cheverud, Patrick Y Jay doi: https://doi.org/10.1101/531988 Abstract Background: In newborns, severe congenital heart defects are rarer than mild ones. The reason why is unknown, but presumably related to a liability threshold that rises with the severity of a defect.
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