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Sukwoon Song

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Articles

Role of phospholipase Cη1 in lateral habenula astrocytes in depressive-like behavior in mice - Experimental & Molecular Medicine

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By Miseon Kang, Ho Yun Lee, Jae-Ick Kim, Min-Ho Nam, Sukwoon Song
| Nature Verified
Abstract Phospholipase C (PLC) enzymes play crucial roles in intracellular calcium-signaling transduction. Several brain PLC subtypes have been extensively studied, implicating them in psychiatric disorders such as depression, epilepsy and schizophrenia. However, the role of the recently identified PLCη remains largely unknown. We found that PLCη1 is prominently expressed in lateral habenula (LHb) astrocytes.
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