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Sumithrra Manivannan on Muck Rack

Sumithrra Manivannan

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Articles

Ventral tegmental area glutamatergic neurons suppress hippocampal ripples and induce head movements in mice

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By Manivannan Subramaniyan, Maggie Zhou Verified, John Dani, Sumithrra Manivannan
| Nature Verified
Abstract Ripples are brief, high-frequency hippocampal oscillations crucial for memory consolidation, occurring predominantly during non-rapid-eye-movement (NREM) sleep. While ripples are generated intrinsically within the hippocampus, growing evidence suggests that their occurrence is modulated by subcortical regions. Whether the ventral tegmental area (VTA)—a subcortical region that directly projects to the hippocampus—regulates ripple activity remains unknown.
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