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Articles by Sun-Young Jun
Three multimodal large language models fail at clinically actionable breast pathology in three different directions
The authors have declared no competing interest. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: The Institutional Review Board of the Catholic Medical Center gave ethical approval for this work (IRB no. OC26RISI0052).
Multi-modal AI for comprehensive breast cancer prognostication
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Abstract Treatment selection in breast cancer is guided by risk assessment using molecular subtypes and clinicopathological characteristics. However, current approaches lack the precision required for optimal clinical decision-making. To address this, we use data from 8161 patients to develop and evaluate an AI test integrating digital pathology with clinical data. The AI test provides a robust method for predicting disease-free interval (C-index: 0.71 [0.68-0.75], HR: 3.63 [3.02-4.37, p < 0.001]).
By Jan Witowski, Ken Zeng, Joseph Cappadona, Jailan Elayoubi, Khalil Choucair, Elena Diana Chiru, Nancy Chan, Young-Joon Kang, Frederick Howard, Irina Ostrovnaya, Carlos Fernandez-Granda, Freya Schnabel, Zoe Steinsnyder, Ugur Ozerdem, Kangning Liu, Waleed Abdulsattar, Yu Zong, Lina Daoud, Anas M. Saad, Frank Yeung, Elisa Liu, Theodore Hill, Benjamin Swett, Danielle N. Rigau, Andrew J. Clayburn, Valerie Speirs, Marcus Vetter, Lina Sojak, Simone Muenst, Daniel Baumhoer, Jia-Wern Pan, Haslina Makmur, Soo-Hwang Teo, Linda M. Pak, Victor Ángel, Dovile Zilenaite-Petrulaitiene, Arvydas Laurinavicius, Brian D. Piening, Carlo B. Bifulco, Sun-Young Jun, Jae Yi, Su Hyun Lim, Adam Brufsky, Francisco J Esteva, Lajos Pusztai, Yann LeCun, Krzysztof J. Geras, Rafic Beydoun, Nitya Thakore, Mohammad Sadic, Natalie Klar
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Nature
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Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma
1. Introduction Uncontrolled cell proliferation via dysregulation of the cell cycle is a hallmark of cancer [1]. Thus, the cell cycle regulation mechanism in cancer is a topic of enormous interest. Cyclin D1, which is encoded by CCND1, is a critical regulator of the G1/S transition and promotes cancer progression in a complex with cyclin-dependent kinase (CDK) 4/6 [2]. Cyclin D1 is overexpressed in various types of cancers; however, findings on its prognostic impact remain inconclusive [3].
Prognostic Potential of Cyclin D1 Expression in Colorectal Cancer
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Analytic performance of PANArray HPV and HPV 9G DNA chip tests for genotyping of high-risk human papillomavirus in cervical ThinPrep PreservCyt samples
Loading metrics Open Access Peer-reviewed Research Article Jiyoung Kim, Sun-Young Jun Jiyoung Kim, Sun-Young Jun Published: October 31, 2019 https://doi.org/10.1371/journal.pone.0224483 Figures Abstract The detection of high-risk human papillomavirus (HR-HPV) is important for early diagnosis of precancerous cervical lesion. The distribution of HR-HPV genotypes in East Asia is different from that in Western countries. HR-HPVs non-16/18 including HPV-58 are highly prevalent in East Asia.
Clinicopathologic and Prognostic Significance of Gallbladder and Cystic Duct Invasion in Distal Bile Duct Carcinoma
Article Citation: Sun-Young Jun, Soyeon An, You-Na Sung, Yejong Park, Jae Hoon Lee, Dae Wook Hwang, and Seung-Mo Hong (2019) Clinicopathologic and Prognostic Significance of Gallbladder and Cystic Duct Invasion in Distal Bile Duct Carcinoma. Archives of Pathology & Laboratory Medicine In-Press.
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