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Sunfu Fan

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Articles

DNMT1-dependent DNA methylation of lncRNA FTX inhibits the ferroptosis of hepatocellular carcinoma

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By Sunfu Fan, Chaodan Shao, Shengnan Jia, Dafei Xie
| dl.begellhouse.com
, DOI: 10.1615/CritRevEukaryotGeneExpr.2024054376 Get access ABSTRACT Hepatocellular carcinoma (HCC) is one of the most malignant solid tumors worldwide. Long non-coding RNAs (lncRNAs) are the key factor in the pathogenesis of HCC. This study aimed to investigate the roles of lncRNA FTX in HCC. mRNA levels were detected using RT-qPCR. Protein expression was determined using western blot. cellular functions were determined using CCK-8 and PI staining assay.
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KDM6A promotes angiogenesis, migration, and invasion of pancreatic cancer via activating LAMP3

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By Liang Xu, Dafei Xie, Yongqi Yu, Sunfu Fan
| dl.begellhouse.com
, DOI: 10.1615/CritRevEukaryotGeneExpr.2024054038 Get access ABSTRACT KDM6A is abnormally expressed in various cancer. This study aimed to investigate the potential of KDM6A in pancreatic cancer (PC). mRNA expression was calculated by RT-qPCR. Protein expression was detected by western blot. Cell viability was measured by CCK-8 assay. Cell angiogenesis was determined by tube formation assay. Cell migration and invasion were determined by transwell assay.
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