Sung Hee Ko on Muck Rack

Sung Hee Ko

As seen in: Nature, Royal Society of Chemistry
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Articles

Rapid Intrahost Diversification and Evolution of SARSCoV2 in Advanced HIV Infection

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By Sung Hee Ko, Pierce Radecki, Frida Belinky, Jinal N. Bhiman
| wits.ac.za
Rapid Intrahost Diversification and Evolution of SARSCoV2 in Advanced HIV Infection
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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIVAD8-EO infection - Nature Communications

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By Joana Dias, Slim Fourati, Xuejun Chen, Cuiping Liu, Chloe A. Talana, Keenan Ernste, Sung Hee Ko, Margaret Lucas, Pierce Radecki, Yoshiaki Nishimura, Malcolm A. Martin, Nicole A. Doria-Rose, Daniel Douek, Rafick-Pierre Sekaly
| Nature Verified
Abstract Anti-HIV-1 broadly neutralizing antibodies (bNAbs) have the dual potential of mediating virus neutralization and antiviral effector functions through their Fab and Fc domains, respectively. So far, bNAbs with enhanced Fc effector functions in vitro have only been tested in NHPs during chronic simian-HIV (SHIV) infection.
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Rapid intra-host diversification and evolution of SARS-CoV-2 in advanced HIV infection - Nature Communications

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By Sung Hee Ko, Pierce Radecki, Jinal N. Bhiman, Susan Meiring, Jackie Kleynhans, Daniel G. Amoako, Margaret Lucas, Stefano Tempia, Reda Rawi, Peter D. Kwong, Nicole Wolter, Anne von Gottberg, Cheryl Cohen
| Nature Verified
Abstract Previous studies have linked the evolution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic variants to persistent infections in people with immunocompromising conditions, but the processes responsible for these observations are incompletely understood. Here we use high-throughput, single-genome amplification and sequencing (HT-SGS) to sequence SARS-CoV-2 spike genes from people with HIV (PWH, n = 22) and people without HIV (PWOH, n = 25).
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