Sunyong Han on Muck Rack

Sunyong Han

As seen in: Nature
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Articles

Experimental evolution under different nutritional conditions changes the genomic architecture and virulence of Acinetobacter baumannii - Communications Biology

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By Ho Sim, Jinki Yeom, Sunyong Han
| Nature
Abstract This study uncovers the molecular processes governing the adaptive evolution of multidrug-resistant (MDR) pathogens without antibiotic pressure. Genomic analysis of MDR Acinetobacter baumannii cells cultured for 8000 generations under starvation conditions (EAB1) or nutrient-rich conditions (EAB2) revealed significant genomic changes, primarily by insertion sequence (IS)-mediated insertions and deletions.
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