Suryyani Deb

1. Introduction Atherosclerosis is a progressive disease characterised by the accumulation of lipids, fibrous materials, and minerals in the arteries, leading to the formation of plaque. Plaque disruption exposes thrombogenic matrix proteins, e.g., von Willebrand factor (VWF), fibrin, fibrinogen, thrombospondin, vitronectin, fibronectin, and collagens, etc., which can recruit and activate circulating platelets.