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Susan Barendrecht on Muck Rack

Susan Barendrecht

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Articles

Reconstituting central nervous system niche cues partially restores homeostatic-like features in cultured murine primary microglia

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By Julia Hahndorf, Benjamin Hietel, Daniel-Christoph Wagner, Martin S. Staege, Holger Cynis, Victoria Ilse, Susan Barendrecht, Stefanie Geissler
| Nature Verified
Abstract Microglia rapidly lose their homeostatic phenotype after isolation, limiting the interpretability of in vitro studies. We systematically evaluated culture conditions that reconstitute central nervous system (CNS) niche inputs to better preserve microglial homeostatic features.
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