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Susan Grimes

As seen in: Nature, Genome Medicine, The Epoch Times, BioRxiv, Pantagraph, Shepherd Express, We The Italians

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Articles

Cancer subclone detection based on DNA copy number in single-cell and spatial omic sequencing data - Nature Methods

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By Chi-Yun Wu, Jiazhen Rong, Anuja Sathe, Billy T. Lau, Susan Grimes
| Nature Verified
Abstract Somatic mutations such as copy number alterations accumulate during cancer progression, driving intratumor heterogeneity that impacts therapy effectiveness. Understanding the characteristics and spatial distribution of genetically distinct subclones is essential for unraveling tumor evolution and improving cancer treatment. Here we present Clonalscope, a subclone detection method using copy number profiles, applicable to spatial transcriptomics and single-cell sequencing data.
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Von Trier Continues to Create Gemütlichkeit

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By Susan Grimes
| Shepherd Express Verified
An East Side institution, Von Trier has occupied the corner of North and Farwell for nearly 50 years. Von Trier is known for an exceptional beer selection and friendly Germanic atmosphere. Generations of Milwaukeeans have bent an elbow under the iconic wrought iron antler chandelier, which once hung in the Pabst mansion. The gorgeous wooden bar is backed with a German mural, and shelves throughout the space display a dizzying array of authentic beer steins.
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November 2024 Milwaukee Book News

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By Susan Grimes
| Shepherd Express Verified
There are many excellent author appearances and book related events this month. Here is just a sampling of these events. Wisconsin author Kevin Kluesner will appear in conversation with Archer Parquette at Boswell Book Company on November 14 at 6:30 p.m. Kluesner will discuss The Killers’ Terms, the third installment in his thrilling Cole Huebsch mystery series.
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