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Articles by Susie Son
High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry
Susie Son, Laura E. Bowie, Tamara Maiuri, Claudia L. K. Hung, Carly R. Desmond, Jianrun Xia and Ray Truant1 From the Department of Biochemistry and Biomedical Research, McMaster University, Hamilton, Ontario L8S 4L8, Canada ↵1 To whom correspondence should be addressed: HSC4N54 1200 Main St. West, Hamilton, Ontario L8N3Z5, Canada. Tel.: 905-525-9140; Fax: 905-522-9033; E-mail: truantr{at}mcmaster.ca.
High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry
High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry Susie Son1, Laura E Bowie1, Tamara Maiuri1, Claudia L.K. Hung1, Carly R Desmond1, Jianrun Xia1 and Ray Truant2* 1McMaster University, Canada 2Biochemsitry and Biomedical Sciences, McMaster University, Canada ↵* Corresponding author; email: truantr{at}mcmaster.ca Author contributions: S.S., C.R.D., and R.T. conceptualization; S.S., L.E.B., C.L.H., and R.T. data curation; S.S., L.E.B., C.L.H.,...
The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components
ABSTRACTAntibiotic resistance is a threat to our modern society, and new strategies leading to the identification of new molecules or targets to combat multidrug-resistant pathogens are needed. Species of the genus Burkholderia, including the Burkholderia cepacia complex (Bcc), Burkholderia pseudomallei, and Burkholderia mallei, can be highly pathogenic and are intrinsically resistant to multiple classes of antibiotics.
The Mla pathway plays an essential role in the intrinsic resistance of Burkholderia cepacia complex species to antimicrobials and host innate components
Antibiotic resistance is a threat to our modern society and new strategies leading to the identification of new molecules or targets to combat multidrug-resistant pathogens are needed. Species of the genus Burkholderia, including Burkholderia cepacia complex (Bcc), Burkholderia pseudomallei, and Burkholderia mallei can be highly pathogenic and are intrinsically resistant to multiple classes of antibiotics.
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