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Potent Racemic Antimicrobial Polypeptides Uncovered by a Stereochemical Series of Cationic d/l Backbones
Abstract Click to copy section linkSection link copied! Antimicrobial polypeptides (AMPs) are often engineered to adopt a secondary structure (e.g., α-helix, β-sheet, or turns), reinforcing the prevailing view that ordered conformations are preferred for enhanced activity.
Antimicrobial Cobaltocenium Copolymers: Tuning Amphiphilicity against NDM-1 Bacteria The emergence of Gram-negative superbugs coupled with a steep decline of antibiotics pipelines has imposed a serious threat to global public health. Cationic metallopolymers have gained significant attention due to their antimicrobial efficacy.
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