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Swarnima Roychowdhury on Muck Rack

Swarnima Roychowdhury

As seen in: MDPI
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Articles

Pharmacodynamic Model of the Dynamic Response of Pseudomonas aeruginosa Biofilms to Antibacterial Treatments

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By Charles Roth, Swarnima Roychowdhury
| MDPI
3. Results A detailed pharmacodynamic model was proposed to describe the dynamic response of Pseudomonas aeruginosa to the antibiotics, tobramycin and colistin (). In this model, the drug first must diffuse through a boundary layer to get to the biofilm. When the drug reaches the biofilm, the biofilm cells go through a progression of transit compartments, the number of which is specific to and reflects the mechanism of action of the drug.
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