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Sylvain Bartolami on Muck Rack

Sylvain Bartolami

As seen in: British Journal of Cancer
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Articles

Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway

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By Ruani Fernando, Claire Perrin-Tricaud, Jade Berthelot, Laurent Cotter, Sylvain Bartolami
| British Journal of Cancer Verified
We found that the apical polarity protein Crb3, one of the mammalian homologues of drosophila Crumbs14, is expressed in the peripheral nerve (Supplementary Fig. 1) and specifically distributes to the microvilli of mSCs. These microvilli are fine cellular protrusions that originate from the outer membrane of the Schwann cell, mix with microvilli of neighbouring cells and contact the node of Ranvier (Supplementary Fig. 2a,e).
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