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Sylvia Mangani

As seen in: Wiley Online Library, MDPI
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Articles

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

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By Sylvia Mangani, Zoi Piperigkou, Konstantinos Spanopoulos
| Wiley Online Library Verified
2D two-dimensional 3D three-dimensional CAFs cancer-associated fibroblasts CTCs circulating tumor cells ECM extracellular matrix EMT epithelial-to-mesenchymal transition GAGs glycosaminoglycans PGs proteoglycans TME tumor microenvironment Cancer progression is strongly influenced by cues arising from interactions within the tumor microenvironment (TME).
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A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

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By Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis
| Wiley Online Library Verified
3D three-dimensional aa amino acid ADAMs a disintegrin and metalloproteinases BMDCs bone marrow-derived cells CMTs chemically modified tetracyclines CTCs circulating tumor cells ECM extracellular matrix EGFR epidermal growth factor receptor EMT epithelial-to-mesenchymal transition EVs extracellular vesicles FAK focal adhesion kinase FGF fibroblast growth factor GAG glycosaminoglycan GPI glycosylphosphatidylinositol HB-EGF heparin-binding EGF-like growth factor IGF-IR insulin-like growth...
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Mimicking the Complexity of Solid Tumors: How Spheroids Could Advance Cancer Preclinical Transformative Approaches

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By Sylvia Mangani, Spyros Kremmydas, Nikos K. Karamanos
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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