Tabea Anne Oswald on Muck Rack

Tabea Anne Oswald

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A feedback circuitry involving γ-actin, β-actin and nonmuscle myosin-2 A controls tight junction and apical cortex mechanics - Nature Communications

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By Marine Maupérin, Jie Yan, Tabea Anne Oswald
| Nature Verified
Abstract Cytoplasmic β- and γ-actin isoforms, along with non-muscle myosin 2 isoforms, are tightly regulated in epithelial cells and compose the actomyosin cytoskeleton at the apical junctional complex. However, their specific role in regulating the mechanics of the membrane cortex and the organization of junctions, and which biomechanical circuitries modulate their expression remain poorly understood.
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