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Taco W. A

As seen in: Nature, Journal of Cell Science
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Articles by Taco W. A

Unconventional model organisms bend our view on mitochondrial cristae Open Access

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By Silje A. C. A, Van Niftrik, Taco W. A
| Journal of Cell Science Verified
Open figure viewer Keywords: Trypanosoma brucei, Toxoplasma gondii, Plasmodium falciparum, Apicomplexa, Kinetoplastida, Mitochondrial cristae, ATP synthase, MICOS, Cardiolipin Subjects: Evolutionary cell biology, Organelles, Parasitology Mitochondria, found in most eukaryotic organisms, are double-membraned organelles with an outer mitochondrial membrane (OMM), which serves as a semi-permeable barrier to the cytoplasm, and an inner mitochondrial membrane (IMM), which surrounds the...
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CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research - Nature Communications

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By Van Gemert, Swiss Tropical, Taco W. A, Nicolas M. B
| Nature Verified
Abstract The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development and differentiates into gametocytes, which are essential for parasite transmission via the mosquito vector. Detailed molecular investigation of gametocyte biology and transmission has been hampered by difficulties in generating large numbers of these highly specialised cells.
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