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Taivan Batjargal

As seen in: BioRxiv
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Articles

Mapping the GDF15 Arm of the Integrated Stress Response in Human Cells and Tissues

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By Kamaryn T. Tanner, Jack Devine, Anna S. Monzel, Taivan Batjargal
| BioRxiv
Abstract Mitochondrial stress activates the integrated stress response (ISR) and triggers cell–cell communication through the secretion of the metabokine growth differentiation factor 15 (GDF15). However, the gene network underlying the ISR remains poorly defined, particularly across metabolically diverse cellular states and tissues.
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