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Takusei Ryu on Muck Rack

Takusei Ryu

As seen in: Frontiers in Physiology
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Articles

Pannexin 3-mediated adenosine triphosphate release from pre-osteoblasts promotes osteoblast differentiation through P2X4 receptor activation

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By Hiroaki Kito, Yohei Yamaguchi, Junko Kajikuri, Susumu Ohya, Ayano Niwa, Takusei Ryu
| Frontiers in Physiology
Abstract Increased pre-osteoblast cell density within bone resorption areas is a key factor in promoting osteoblast differentiation; however, the molecular mechanisms underlying this process remain poorly understood. In this study, we investigated the role of ATP release and purinergic receptor P2X4 signaling in osteoblast differentiation using the murine pre-osteoblastic cell line MC3T3-E1.
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