Talia P Sukienik on Muck Rack

Talia P Sukienik

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Engineering an fgfr4 knockout zebrafish to study its role in development and disease

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By Emma Harrison, Amanda Jay, Matthew Kent , Talia P Sukienik
| biorxiv.org
Abstract Fibroblast growth factor receptor 4 (FGFR4) has a role in many biological processes, including lipid metabolism, tissue repair, and vertebrate development. In recent years, FGFR4 overexpression and activating mutations have been associated with numerous adult and pediatric cancers. As such, FGFR4 presents an opportunity for therapeutic targeting which is being pursued in clinical trials.
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