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Articles

Contribution of different relapse phenotypes to disability in multiple sclerosis

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By Tim Spelman, Eva Havrdova, Tamasine Stewart, Dana Horakova
| SAGE Publishing
This study evaluated the effect of relapse phenotype on disability accumulation in multiple sclerosis. Analysis of prospectively collected data was conducted in 19,504 patients with relapse-onset multiple sclerosis and minimum 1-year prospective follow-up from the MSBase cohort study. Multivariable linear regression models assessed associations between relapse incidence, phenotype and changes in disability (quantified with Expanded Disability Status Scale and its Functional System scores).
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