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Tan Hui Ying on Muck Rack

Tan Hui Ying

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Articles

A microbiome meta-transcriptomics pipeline identifies a neutrophil elastase inhibitor that protects the colonic epithelial barrier

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By Jake P. Violi, Brett A. Neilan, Simon Keely, William Donald, Carlos Riveros, Gerard E. Kaiko, Bojan Stojkovic, Matthijs Bekkers, Tan Hui Ying
| Nature Verified
Abstract Inflammatory Bowel Diseases (IBD) are lifelong conditions. Current therapeutic approaches target inflammatory signalling rather than improving barrier permeability or repair. The gut microbiome provides an exciting opportunity for novel drug discovery to leverage its role in healthy gut homeostasis. There is a clear need to identify bioactive molecules within the microbiota that could protect the intestinal barrier.
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