Tangbin Hu on Muck Rack

Tangbin Hu

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Articles

SETDB2 induces abnormal SHP-1 splicing and promotes immunosuppression in hepatocellular carcinoma

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By Qinlian Jiao, Yidan Ren, Xin Su, Yuxuan Cai, Yunshan Wang, Guangyong Zhang, Miaoqing Zhao, Maoxiao Feng, Zigan Li, Tangbin Hu
| Nature Verified
Abstract The clinical application of targeted therapy and immune checkpoint inhibitors (ICIs) has significantly improved the survival prognosis of patients with hepatocellular carcinoma (HCC). However, due to the high heterogeneity of HCC, the response rate to immunotherapy is still low, and there is an urgent need to identify reliable biomarkers and potential therapeutic targets to improve the therapeutic benefit.
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