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Taoliang Chen on Muck Rack

Taoliang Chen

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Articles

B3GNT9-mediated O-glycosylation reprograms fatty acid metabolism in peroxisomes to promote invasion progression of peritumoral glioma cells

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By Zechuan Peng, Jiasheng Zhong, Yunhe Zhao, Jie Liu, Fei Wu, Zetao Chen, Tianwei Wang, Yiquan Ke, Shengsong Fu, Taoliang Chen
| Nature Verified
Abstract Glioblastoma (GBM) is a highly aggressive brain tumor characterized by rapid recurrence and invasion, particularly in the peritumoral brain zone (PBZ), a critical site for tumor spread. Through RNA-seq of tumor core and PBZ tissues from GBM patients, we identified B3GNT9 as significantly upregulated in tumor cells within the PBZ. Bioinformatics analysis revealed that elevated B3GNT9 expression is associated with poor prognosis.
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