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Tarza J. Siahmansur on Muck Rack

Tarza J. Siahmansur

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Effect of Extended‐Release Niacin on High‐Density Lipoprotein (HDL) Functionality, Lipoprotein Metabolism, and Mediators of Vascular Inflammation in Statin‐Treated Patients

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By Rahul Yadav Verified, Jonathan Schofield, Yifen Liu, See Kwok, Salam Hama, Michael France, Ruth Eatough, Phil Pemberton, Tarza J. Siahmansur, Rayaz Malik, Basil A. Ammori, Basil Issa, Naveed Younis, Rachelle Donn, Adam Stevens, Paul Durrington
| jaha.ahajournals.org
Background The aim of this study was to explore the influence of extended‐release niacin/laropiprant (ERN/LRP) versus placebo on high‐density lipoprotein (HDL) antioxidant function, cholesterol efflux, apolipoprotein B100 (apoB)‐containing lipoproteins, and mediators of vascular inflammation associated with 15% increase in high‐density lipoprotein cholesterol (HDL‐C). Study patients had persistent dyslipidemia despite receiving high‐dose statin treatment.
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