Tavian Bowen-Moore on Muck Rack

Tavian Bowen-Moore

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Articles

Multi-ancestry gene expression models amplify transcriptome-wide association study discovery and validation

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By Xavier Bledsoe, Nathan Watkins, Ravi Shah, Eric R. Gamazon, Tavian Bowen-Moore, Marlisa Shaw
| Nature Verified
Abstract Our understanding of the influence of ancestral background on genetically determined expression remains limited, especially when gene expression models are applied to studies from different or multiple populations. We perform transcriptome-wide association studies of 6 psychiatric conditions, leveraging gene expression models trained in cohorts with different proportions of African, European, and Indigenous American genetic ancestries.
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