Tayden Li on Muck Rack

Tayden Li

As seen in: Nature, medRxiv
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Articles

Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disorders - Communications Medicine

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By Madeleine Salem, Tayden Li, Brittany Mitchell, Hanyang Shen, Scott Gordon, Ciera Stafford, Andrew Ratanatharathorn, Joeri J. Meijsen, Charles Kooperberg, Karestan C. Koenen, Nicholas Martin, Mytilee Vemuri
| Nature Verified
Abstract Most women experience hot flashes (hot flushes) during the menopause transition. Menopausal hot flashes typically persist for years, and for a sizeable minority of women, are substantially impairing. Genetic investigations can improve understanding of hot flash etiology. We conducted a trans-ancestry genome-wide association study (GWAS) of hot flashes (N = 149,560) among post-menopausal women age 35-88.
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Mapping the cellular etiology of schizophrenia and complex brain phenotypes - Nature Neuroscience

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By Laramie Duncan, Tayden Li, Madeleine Salem, Will Li, Leili Mortazavi, Hanyang Shen, Jacob Ballon, Longzhi Tan, Brian Knutson, Karl Deisseroth, Brandon Scott Pruett
| Nature Verified
Abstract Psychiatric disorders are multifactorial and effective treatments are lacking. Probable contributing factors to the challenges in therapeutic development include the complexity of the human brain and the high polygenicity of psychiatric disorders. Combining well-powered genome-wide and brain-wide genetics and transcriptomics analyses can deepen our understanding of the etiology of psychiatric disorders.
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Mapping the Cellular Etiology of Schizophrenia and Diverse Brain Phenotypes

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By Laramie Duncan, Will Li, Tayden Li, Madeleine Salem
| medRxiv
The authors have declared no competing interest. This work was supported by the Jaswa Innovator Award to LD and by the National Institute of Mental Health (NIMH) to LD (R01 MH123486 & R21 MH125358). I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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