Abstract Deep brain stimulation (DBS) is an established therapy for advanced Parkinson’s disease (PD), but its long-term social and clinical impact has not been well characterized in large cohorts. We conducted a retrospective cohort study using a nationwide hospital database across the United States. Among 79,845 adults hospitalized with PD in 2018 and followed through 2023, 482 underwent DBS implantation. Overlap propensity score weighting was used to balance baseline characteristics.