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Whole-Cell Phenotypic Screening of Medicines for Malaria Venture Pathogen Box Identifies Specific Inhibitors of Plasmodium falciparum Late-Stage Development and Egress

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By Meenakshi A. Belekar, Alok Tanala Patra, Tejashri Hingamire, Aoli Xiong
| asm.org
Experimental Therapeutics Alok Tanala Patra, Tejashri Hingamire, Meenakshi A. Belekar, Aoli Xiong, Gowtham Subramanian, Zbynek Bozdech, Peter Preiser, Dhanasekaran Shanmugam, Rajesh Chandramohanadas DOI: 10.1128/AAC.01802-19 ABSTRACT We report a systematic, cellular phenotype-based antimalarial screening of the Medicines for Malaria Venture Pathogen Box collection, which facilitated the identification of specific blockers of late-stage intraerythrocytic development of Plasmodium falciparum.
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