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Articles by ten Berg
Antithrombotic therapy after percutaneous coronary intervention in patients with atrial fibrillation: an individual patient data network meta-analysis
Randomized trials demonstrated that in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) direct oral anticoagulants (DOAC) and a P2Y12 inhibitor reduce bleeding compared with vitamin K antagonist (VKA) plus dual antiplatelet therapy (DAPT) with no increase in ischemic risk; however, important gaps in knowledge remain, limiting certainty and generalizability of these findings.
The year in cardiovascular medicine 2024: the top 10 papers in thrombosis and antithrombotic treatment
In 2024 many papers have enriched our understanding of common thrombotic diseases and their management. Some consolidate our current practice, others entreat us to use moderation, others still, define emerging or future developments (Graphical Abstract). Patients with atrial fibrillation (AF) and chronic coronary syndromes (CCSs) are at excess risk of bleeding when long-term anticoagulation is combined with antiplatelet therapy.
2023 European Society of Cardiology guidelines for the management of acute coronary syndromes - Netherlands Heart Journal
Abstract This review discusses the new recommendations in the 2023 European Society of Cardiology guidelines on the management of acute coronary syndrome and provides a perspective on topics specific to clinical practice in the Netherlands, including pre-treatment, antiplatelet agent strategies, the use of risk scores and logistical considerations with regard to the timing of coronary angiography. Discover the latest articles, news and stories from top researchers in related subjects.
The puzzle of antiplatelet therapy in ACS: ticagrelor monotherapy is another missing piece
This editorial refers to ‘Ticagrelor monotherapy for acute coronary syndrome: an individual patient data meta-analysis of TICO and T-PASS trials’, by Y.-J. Lee et al., https://doi.org/10.1093/eurheartj/ehae249. The foundation for the routine use of aspirin in patients with acute coronary syndromes (ACS) was established during the 1980s.
Reply to ‘Revisiting postsurgical aortic pseudoaneurysm mortality and treatment options’ - Netherlands Heart Journal
We appreciate Mr Bervoets’ interest [1] in our recent publication in the Netherlands Heart Journal [2]. However, the key point of our study design is overlooked. This is a case series, which is defined by observations made on a series of individuals, who usually all receive the same intervention; there is no control group.
The year in cardiovascular medicine 2023: the top 10 papers in thrombosis and antithrombotic treatment
Preventing thrombosis while minimizing bleeding is paramount in antithrombotic therapy. Recent progress has brought this goal closer. This Viewpoint highlights recent pivotal papers on antithrombotic strategies, with findings summarized in the Graphical Abstract.
Comparison of the effects of the GPIIb-IIIa antagonist Zalunfiban and the P2Y12 antagonist Selatogrel on Platelet Aggregation
Journal of Thrombosis and Thrombolysis, Aug 2023 Understanding the pharmacodynamic effects of platelet inhibitors is standard for developing more effective antithrombotic therapies. An example is the antithrombotic treatment of acute coronary syndrome (ACS), in particular ST-elevated myocardial infarction (STEMI) patients who are in need for rapid acting strong antithrombotic therapy despite the use of aspirin and oral P2Y12-inhibitors.
Shorter laboratory turnaround time is associated with shorter emergency department length of stay: a retrospective cohort study
BMC Emergency Medicine, Dec 2022 This is a preview of a remote PDF: https://bmcemergmed.biomedcentral.com/counter/pdf/10.1186/s12873-022-00763-w Vrijsen, Bram E. L., Haitjema, Saskia, Westerink, Jan, Hulsbergen-Veelken, Cornelia A. R., van Solinge, Wouter W., ten Berg, Maarten J.. , BMC Emergency Medicine, 2022, pp. 1-7, Volume 22, Issue 1, DOI: 10.1186/s12873-022-00763-w
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Randomized Trial of Primary PCI with or without Routine Manual Thrombectomy
Study Design The Trial of Routine Aspiration Thrombectomy with PCI versus PCI Alone in Patients with STEMI (TOTAL) was an international, investigator-initiated, multicenter, prospective, randomized trial of upfront manual aspiration thrombectomy with the Export catheter (Medtronic) versus PCI alone. This was an open trial with blinded adjudication of outcomes.
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