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Teoni C. Antonopoulos on Muck Rack

Teoni C. Antonopoulos

As seen in: Taylor & Francis Online
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Articles

Global distribution of CYP2C19 variants in clopidogrel-indicated populations: implications for pharmacogenomic-guided antiplatelet therapy

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By Josephine Hughes, Ruby Soueid, Teoni C. Antonopoulos
| Taylor & Francis Online
ABSTRACT Clopidogrel is a widely prescribed antiplatelet prodrug, with activation affected by CYP2C19 loss- and gain-of-function variants. Whilst global CYP2C19 variant prevalence is well described, this scoping review characterises CYP2C19 diplotype and metaboliser phenotype frequencies in clopidogrel-indicated populations. A literature search of Scopus, PubMed, Ovid MEDLINE, and Ovid Embase was conducted from inception to 6 July 2026.
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