Thai Red Cross

Introduction Leptospirosis is a globally prevalent cause of acute undifferentiated febrile illness (AUFI) that poses significant diagnostic challenges in its early stages. Based on a comprehensive systematic review of published studies and national databases from 34 countries, Costa et al. estimated that leptospirosis causes approximately 1.03 million cases and 58,900 deaths each year worldwide1.

Abstract Systems thinking approaches can determine system interdependencies to guide effective policymaking but have been underutilised in health policymaking, particularly for policies related to access and delivery of health services. In Thailand, a policy changing access to dialysis services for patients with kidney failure in 2022 had resulted in an unexpected surge in patients, mortality rate, and budget overspend.

Loading metrics Open Access Peer-reviewed Research Article Abstract Background & objectives Cirrhosis patients with worsening of the liver function are defined as acute decompensation (AD) and those who develop extrahepatic organ failure are defined as acute-on-chronic liver failure (ACLF). Both AD and ACLF have an extremely poor prognosis. However, information regarding prognostic predictors is still lacking in Asian populations.