Thamonpan Laocharoensuk

Abstract Highly pathogenic avian influenza A(H5N1) virus exhibits a strong tropism for the bovine mammary gland, challenging our understanding of influenza A virus host range and tissue specificity. We performed experimental studies with an influenza A(H5N1) B3.13 genotype virus in female lactating dairy cattle to define the infectious dose, routes of exposure, and factors linked to morbidity and mortality.

Abstract Hepatitis E virus (HEV) is an expanding zoonotic viral disease threat. Although HEV causes acute viral hepatitis, it is increasingly being recognized as a systemic pathogen with detection and damage in extrahepatic tissues. The presence of HEV RNA in the semen of chronically infected human patients in the absence of viremia and fecal shedding and presence of HEV in the sperm head underscores the need to understand the interaction of HEV within the male reproduction system.

Citation: Yadav KK, Boley PA, Laocharoensuk T, Khatiwada S, Lee CM, Bhandari M, et al. (2024) Infectious hepatitis E virus is associated with the mature sperm head. PLoS Pathog 20(5): e1012240. https://doi.org/10.1371/journal.ppat.1012240 Editor: Qiang Ding, Tsinghua University, CHINA Received: January 30, 2024; Accepted: May 4, 2024; Published: May 20, 2024 Copyright: © 2024 Yadav et al.